Nephalion was one of the sons of Minos (with Eurymedon, Chryses and Philolaüs). All four were killed by Heracles when they murdered two of his crew (on his visit to the Amazons, when he put in at the island of Paros).

His name seems to mean 'sober', 'abstemious', from nephalios, 'drinking no wine'. Nephalia meiligmata, literally 'wineless propitiations', were offerings of water, milk and honey made to the Eumenides. (The second word in the phrase is related to meli, 'honey' and therefore to the name Melissa)